cancer mesothelioma

Silent Killer Cancer Mesothelioma |Deciduoid mesothelioma | Be safe in 2022

Cancer Mesothelioma is one type of cancer of mesothelioma, there is a membrane lined inside a body cavity, such as in the abdomen or chest. Mesothelioma starts in three out of every four chest cavities. Mesothelioma can also be started in the abdominal cavity and around the heart.

Mesothelioma is one type of cancer caused by asbestos. It usually occurs in the lining of the lungs or abdomen. The average lifespan of patients after diagnosis is 18 – 31 months. But the prognosis may be improved with the treatment of mesothelioma. 

Symptoms may include 

  • chest pain
  • shortness of breath and 
  • general fatigue.

Reason for Cancer Mesothelioma: Asbestos

What are the main causes of cancer mesothelioma?

Exposure to Asbestos is the leading cause of pleural mesothelioma. About 80 percent of people with mesothelioma have been exposed to asbestos. When someone inhales asbestos fibers, the fibers travel to the ends of the small airways and reach the pleura. There they can cause inflammation and scarring.

From wherever they originate, malignant cells from the mesothelium can invade or attack and cause damage to nearby tissues. Cancer cells can be metastasized or spread out to other organs or parts of the body.It another cause of cancer mesothelioma .

Sometimes mesothelioma is diagnosed, the disease continues progressing. The survival rate of 5 years is about 5% to 10%. Most of the patients with pulmonary mesothelioma die as a result of respiratory failure or pneumonia. Slowly the tumor spreads out through the diaphragm; some patients feel obstruction of the small intestine, a muscle that separates the chest and abdominal cavity. 

A small portion of people dies because of heart complications when the tumor invades or attacks the pericardium – a thin sac that surrounds the heart.

The main cause or risk factor for cancer mesothelioma is working with asbestos. Asbestos is a group of minerals with thin microscopic fibers. Since these fibers are resistant to heat, fire, and chemicals and do not conduct electricity, asbestos has been mined and widely used in construction, automotive, and other industries.

In manufacturing areas If tiny asbestos fibers are released into the air, they can be inhaled or swallowed resulting in serious health problems. About 75% of cancer mesothelioma cases may be associated with exposure to asbestos at work. There is much evidence that people living with family members and other asbestos workers are at risk for mesothelioma and possibly many other asbestos-related diseases. This may be caused by exposure to asbestos dust brought into the clothing and hair of manufacturing workers. Cancer Mesothelioma has also been reported in people who live near asbestos mines areas.

However, cancer mesothelioma has been reported in some individual people without any known exposure to asbestos. 

Other possible causes may be:

Zeolites :

These minerals are chemically related to asbestos. According to the American Cancer Society, one of these related minerals, erionite, is common in the soil in some parts of Turkey. Exposure to erionite is thought to be responsible for the high rates of mesothelioma in that region. It another cause of cancer mesothelioma .

Radiation:

The American Cancer Society notes that there have been several published reports of mesotheliomas occurring after exposure to high levels of radiation in the chest or abdomen or injections of thorium dioxide (thorotrust), a substance used by doctors in some chest X-rays.It another cause of cancer mesothelioma .

SV40 virus :

According to the American Cancer Society, some studies in laboratory animals have raised the possibility that infection with Simian virus 40 (SV40) may increase the risk of mesothelioma. Some of the injectable polio vaccines given between 1955 and 1963 were contaminated by the SV40, which infected about 30 million people in the United States. So far, the largest studies to address this problem in humans have not found an increased risk for mesothelioma or other cancers in people receiving the vaccine as a child.It another cause of cancer mesothelioma .

Genetics :

Some experts believe that some people may be genetically predisposed to mesothelioma. Disease rates vary by population.It another cause of cancer mesothelioma .

Symptoms of mesothelioma

Cancer Mesothelioma symptoms are not usually seen for 20 to 50 years after initial asbestos exposure.

Cancer Mesothelioma
Cancer Mesothelioma

The main symptoms of pulmonary mesothelioma are shortness of breath and chest pain. Fluid accumulation in the pleura caused by mesothelioma, if large enough, can also contribute to shortness of breath.

Symptoms of peritoneal mesothelioma may include:

  • Weight loss
  • Swelling and pain in the abdomen
  • Blood clotting abnormalities
  • Intestinal obstruction
  • Anemia
  • Fever

If cancer has spread to other parts of the body, the symptoms may include pain, difficulty swallowing, or swell up  the neck or the mouth.

Since many conditions share these symptoms, having these symptoms does not mean that you have mesothelioma. It is important to see your doctor determine what causes them. Medical history and physical examination

Because cancer mesothelioma is abnormal, it and early often misdiagnosis. If you have symptoms that suggest you may have cancer mesothelioma, your doctor will probably take a complete medical history of the symptoms and possible things that increase your risk of developing the disease, especially to test ray asbestos exposure.Eexposure to Asbestos is the Number 1 thing that makes mesothelioma more promising.

Your doctor will also ask about your general health and examine to check for possible symptoms for mesothelioma. These are generally retention of fluid in the chest cavity, abdomen, or pericardium (Pericardium is the thin membrane which cover the heart).

Depending on the test results, your doctor may refer you for a cancer mesothelioma test.

Tests for mesothelioma

There are different types of cancer mesothelioma tests. These include:

Blood tests.

Blood levels of three substances – fibulin-3, osteopontin, and soluble mesothelin-related peptides (SMRP) – are often higher in people with mesothelioma. Although these blood tests cannot confirm the diagnosis of mesothelioma – further studies are needed before they can be used reliably in a clinical setting – high levels of this substance make the disease more probable.

Test the fluid and tissue samples.

If fluid accumulates in your body which may be related to cancer mesothelioma, your doctor may remove a sample of the fluid by inserting a needle through the skin at the site of fluid formation. The fluid of the region is tested under a microscope. If cancer cells are observed through, further tests will be performed for better understand if the cancer is mesothelioma.

This test goes by different names depending on where the fluid is:

  • Thoracentesis – Chest cavity
  • Paracentesis – Stomach
  • Pericardiocentesis – The membrane around the heart

Even if your doctor doesn’t find mesothelioma cells in the fluid, that doesn’t mean you don’t have mesothelioma. Sometimes an actual tissue sample (biopsy) is needed to diagnose cancer mesothelioma.

Biopsy.

There are ways to remove tissue to test for cancer mesothelioma. They also include:

Needle biopsy.

This involves inserting a long, hollow needle through the skin to remove a small piece of the tumor. Your doctor may use imaging tests to guide the needle into the tumor. In some cases, the sample may be too small for diagnosis and a more invasive procedure may be required.

Thoracoscopy, laparoscopy, and mediastinoscopy.

In this procedure, the doctor inserts a thin, illuminated opportunity through a small incision in the skin to see potential areas of mesothelioma. Smaller tools placed through other cuts can be used to remove pieces of tissue for examination under a microscope. The specific procedure depends on the area being tested:

Thoracoscopy test means the examiner of the space between the lungs and chest wall.

Laparoscopy test means the examiner of the inside of the abdomen.

Mediastinoscopy test means the examiner of the center of the chest, around the heart.

Surgical biopsy.

In some cases, more invasive procedures may be needed to obtain a tissue sample large enough to diagnose. In that case, a surgeon may perform a thoracotomy (opening of the chest cavity) or laparotomy (opening of the abdominal cavity) to remove a large sample of the tumor or the entire tumor.

Endobronchial ultrasound-guided biopsy.

This process is generally passing a long, thin, flexible tube down through the throat to examine the lungs for tumor cells. The tube  contains an ultrasound, so the doctor can better identify the tumor and the appropriate site for a biopsy. If a tumor is observed, the doctor can remove a small portion or sample of it through a tube.

Imaging test.

These tests allow your doctor to look inside your body without cutting. Commonly used imaging tests to diagnose cancer mesothelioma include:

Chest X-ray. X-rays of the chest may show abnormal thickening or accumulation of calcium in the lining of the lungs, changes in the fluid or lungs between the lungs and the wall of the chest, which may indicate cancer mesothelioma.

Computed tomography (CT).

A CT scan is a procedure that uses multiple X-rays and a computer to create detailed images of the inside of the body. CT scans are often used to look for signs of cancer, to find out where the cancer is, and to see if cancer has spread.

Positron emission tomography (PET).

This test involves giving a shot of a compound containing a radioactive atom and then taking a picture of the body. Cancer cells absorb large amounts of radioactive compounds and appear brighter than normal tissue in the images. Doctors then focus on further testing in these areas of potential cancer.

Magnetic Resonance Imaging (MRI).

 MRI scans use radio waves and powerful magnets to create detailed images of the body. Since they provide detailed images of soft tissues, they can help your doctor find out where the tumor is. For mesotheliomas involving the diaphragm (a dome-shaped muscle below the lungs), MRI scans may be particularly effective. The prognosis for mesothelioma

Some things affect your options for diagnosing mesothelioma as well as a mesothelioma treatment. They include the following:

Stage of cancer, or stage of cancer in the body. The stage is usually based on the size of the tumor, whether there are cancer cells in the lymph nodes, and whether cancer has spread beyond its original location.

  • MesothelYour size
  • Whether cancer mesothelioma can be completely removed by surgery
  • The amount of fluid in the chest or abdomen
  • Your age and general health
  • Mesothelioma cell type
  • Whether cancer has just been diagnosed or has already been treated and returned

Treatment of mesothelioma

Treatment of mesothelioma depends on many factors including the above.

Cancer Mesothelioma
Cancer Mesothelioma

Three standard types of treatment are used:

  • surgery,
  • radiation, and
  • chemotherapy.

 Mesothelioma treatment often involves two or three combinations.

Surgery:

The major surgeries used to treat cancer mesothelioma are:

• Wide local incision, which removes cancer along with some healthy surrounding tissue

• Pleurectomy and decoration, where the surgeon removes the lining of the lungs, the lining of the chest, and the outer surface of the lungs.

• Extrapular pneumonectomy, which involves the removal of a complete lung and thoracic lining, the diaphragm, and the sac lining around the heart.

• Pleurodesis, which uses chemicals or drugs to create scars on the lining of the lungs and stick to the lungs. Stains stop the accumulation of fluid. It is used to control symptoms and not to cure them.

Radiation therapy:

Treatment of this type of cancer uses high-energy X-rays and other types of radiation to kill or prevent mesothelioma cells from growing. Radiation can be given externally or internally. External radiation therapy uses a machine outside the body to send radiation towards cancer. Internal radiation uses a radioactive substance that is sealed in needles, seeds, wires, or catheters that are placed directly in the area near the mesothelioma.  It is also referred as pericardial mesothelioma radiology

Chemotherapy:

It uses drugs to stop the growth of cancerous mesothelioma cells, either by killing the cells or by stopping their division. Chemotherapy can be given by mouth, injected into a vein or muscle to enter the bloodstream and reach the mesothelioma cells throughout the body, or it can be placed directly on the affected area of ​​the body to primarily affect the mesothelioma cells in that area. Sometimes, doctors use multiple chemotherapy drugs. This is called combination chemotherapy.

Immunotherapy:

It uses some drugs to help your immune system fight cancer. The combination of nivolumab (Opdivo) and ipilimumab (Yervoy) is approved by the FDA for irreversible mesothelioma. It is mesothelioma that has spread to a large part of the body and cannot be treated surgically.

Tumor-treated field (TTF). This type of treatment uses electric fields, including chemotherapy and specific frequencies, to slow down cancer cell division.

It is very much successful mesothelioma treatment in germany  .

New mesothelioma treatment options

The followings are new treatment of mesothelioma .

new mesothelioma treatment options
new mesothelioma treatment options /treatment of mesothelioma
Cancer Mesothelioma
Cancer Mesothelioma

What is Deciduoid mesothelioma ?

Deciduoid mesothelioma is a special type of cancer which is an uncommon subtype of epithelioid mesothelioma . Deciduoid mesothelioma  is characterized by the presence of cytomorphological features resembling decidua or decidualized tissue. The first case of this mesothelioma variant is observed in 1985.The disease arose in the peritoneum of a 13-year-old girl who had primarily been diagnosed and treated as having diffuse pseudotumoral deciduosis. This patient was died 8 months after the diagnosis of Deciduoid mesothelioma.

Is mesothelioma always fatal?

Malignant cancer mesothelioma is considered an invasive and deadly disease. Most mesothelioma patients survive about 12 months after diagnosis. There is no cure for this cancer, but with treatment, patients have extended their life beyond their initial prognosis.

How does a person get mesothelioma?

Mesothelioma is caused by asbestos exposure. When asbestos fibers are inhaled or eaten, they cause scarring and inflammation, which can lead to mesothelioma. A mesothelioma tumor usually takes decades to develop after initial asbestos exposure.

What are the early warning signs of mesothelioma?

  • Symptoms of pleural mesothelioma (chest mesothelioma)
  • Pain in the side of the chest or lower back.
  • Weakness of breath.
  • Cough.
  • Swallowing problems (feeling like food getting stuck)
  • Roughness.
  • Swelling of face and arms.

Is mesothelioma a painful death?

Cancer Mesothelioma is serious cancer with a bad prognosis. For many patients, mesothelioma is a painful disease. Asbestos cancer pain is often caused by tumors that put pressure on vital organs and nerves. As the disease worsens, fluid may accumulate in the chest or abdomen, making it difficult to breathe or eat.

Has anyone survived mesothelioma?

Mesothelioma survival rate – Cancer Mesothelioma survival rate is usually 4-18 months after diagnosis, but patients with mesothelioma survive for more than 10 years. The current five-year survival rate for this disease is only 10 percent.

Can you be cured of mesothelioma?

Unfortunately, mesothelioma is often an invasive disease and is not curable for most people. Mesothelioma is usually diagnosed at an advanced stage – when it is not possible to remove cancer through surgery. Instead, your doctor can work on controlling your cancer to make you more comfortable.

Can smoking cause mesothelioma?

By itself, smoking does not increase the risk of mesothelioma, but a combination of smoking and asbestos exposure can increase the risk of certain types of lung cancer. Radiation exposure. Radiation exposure can result in mesothelioma, such as a patient who has previously received radiation therapy for lymphoma.

Who is most at risk for mesothelioma?

The risk of mesothelioma increases with age. Mesothelioma can occur in young people (even children), but it is rare in people under 45 years of age. 2 out of 3 people with chest mesothelioma are 65 or older.

Where does mesothelioma start?

Pleural mesothelioma begins in the chest around the lungs. This is by far the most common type. Peritoneal mesothelioma begins in the abdomen or lining of the abdomen. Pericardial mesothelioma begins in the lining of the heart.

How fast does mesothelioma progress?

 There is a long latency period associated with mesothelioma, which means it can take 10 to 50 years for symptoms to appear. The latency period varies with each case of mesothelioma and depends on many factors such as the age and length of a person’s exposure to asbestos.

Can mesothelioma go into remission?

Mesothelioma remission occurs when there are no visible signs of cancer in the body. Although it is rare, some patients have reached short-term or long-term mesothelioma remission through multiple treatments.

Many youtube videos are available about mesothelioma . You watch the video to known more:

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